Giuliana Rancic has been very vocal about her desires to have another baby. Along with her husband Bill, the 40-year-old television presenter made a confession to Life & Style Magazine that she and Bill have only one frozen embryo left? So, is Giuliana losing hope to have a second child?

Giuliana and Bill Rancic have been very open about wanting to have another baby as well as their struggles with infertility. According to The Daily Mail, the E! News host may still have one last chance to give their two-year-old son, Edward Duke, a baby brother or sister.

"This could be our last shot," Giuliana told the mag. "We're keeping our fingers crossed that everything works out."

The couple, Giuliana and Bill Rancic have been struggling for years-long fertility before they had their first baby, first-born son Duke, who was born via a surrogate in 2012. Unfortunately in 2014, the said surrogate suffered a miscarriage while pregnant with the couple's second child in 2014, Star Pulse revealed.

In the past week, Giuliana Rancic has been greatly criticized over an offensive comment she made on her television show, "Fashion Police." However, Giuliana remained optimistic and hasn't given up the hope of having another baby. In an exclusive interview with In Touch, the famous TV host confided that she will stay positive no matter what the outcome.

"If I don't have another kid," she says, "I have to remind myself that I'm very, very fortunate to have what I have. I have Duke and he's healthy and hilarious. He's just a mini-Bill and so delicious!"

Rancic also revealed that she is not giving up on getting pregnant. And though the possibility of getting pregnant is a long shot since she's currently on medication until she reached the age of42, Giuliana Rancic will still try her best to have baby.

But aside from the racist comments and baby issues, Giuliana Rancic is also facing unending controversies and rumors about her weight loss. As per The Examiner, it started when people noticed her super-skinny figure during the 2015 Golden Globe Awards and the Grammys. Some even claimed that she's anorexic.

However, Rancic slammed the rumors of being too skinny in an interview with In Touch Weekly, MStarz revealed. Giuliana Rancic also cited a comment someone wrote about her not wanting to carry a baby in fear of gaining weight.

"I read a comment on some article, 'She doesn't want to carry a baby ... because she doesn't want to get fat,'" Giuliana stated. "I'm like, how disgusting is that? How about I'm on medication that prevents me? It's just awful."

Though Giuliana Rancic had faced some trials in her life, including breast cancer and fertility issues, she stayed hopeful and positive about having another baby.