Grey's Anatomy Season 10 spoilers involve the premiere date of the medical drama series on September 26. Even if the first episode is still a month away, Shonda Rhimes, creator of the show, revealed some facts about Season 10. The first question was whether or not this will be the last season of the show.

Patrick Dempsey who plays Dr. Shepherd had made comments about how he has been in the series long enough. With this comment, fans tried to figure out what he meant. Did he hint that this will be the last season for the show? Is he going to leave the show? And if he would leave, what would happen to the show?

Although Rimes did not comment on any departure of any characters, she did hint that there will be some trouble with regard to the unlikely couple of Callie Torres and Arizona Robbins.

"It's one thing to be cheated on by a spouse once, it's another thing to have it happen a second time," Rhimes told The Hollywood Reporter. Loyal fans are wondering whether the two will get a divorce in Grey's Anatomy Season 10. Rhimes also added, "We're going to get to see a very interesting journey for both women."

Another fact that Rhimes shared is about Dr. Meredith Grey and Dr. Derek Shepherd. "Meredith has two children now, and it's the first time (Meredith and Derek) had a newborn, so that's going to be very different for as well. Their relationship is in a good place, but it's going to hit a complex place," Rhimes shared.

Grey's Anatomy have come a long way. Some people comment that the writers have tried every straw there is in the medical drama. Dempsey commented "When you're in a long show, there's less discovery and more of an endurance of having to be present."

Is Grey's Anatomy Season 10 the end of the series? Rhimes said that she would continue the series as long as she can come up with stories for it.